Clinical characterization of Post-axial Polydactyly

Authors

  • Mir Chakar Rahim Institute of Biochemistry, University of Balochistan, Quetta, Pakistan
  • Wajid Ali Institute of Biochemistry, University of Balochistan, Quetta, Pakistan
  • Abdul Samad Department of Botany, University of Balochistan, Quetta, Pakistan
  • Sirmast Faiz Dr. Panjwani Centre for Molecular Medicine and Drug Research, Karachi, Pakistan

DOI:

https://doi.org/10.6084/rjas.v1i2.390

Keywords:

clinical variabilities, non-syndromic, Post-axial Polydactyly

Abstract

Polydactyly is among the most common congenital limb malformations, presenting at an estimated incidence of 1 in approximately 700–1,000 live births. Clinical manifestation of polydactyly remains poorly understood because of their phenotypic variabilities and genetic diversity. Prenatal ultrasound screening can detect polydactyly and can alert the health care worker and the pregnant woman to proceed with further anomaly screening to exclude possible concomitant anomalies The aim of this review is to provide an overview of the genetic basis of non-syndromic post axial polydactyly(PAP) and discuss the role of biological pathways in non-syndromic PAP to help clinicians understand and characterize the disease.

Author Biography

  • Mir Chakar Rahim, Institute of Biochemistry, University of Balochistan, Quetta, Pakistan

    Mir Chakar Rahim, Wajid Ali and Abdul Samad are MPhil research student at University of Balochisan, Quetta, Pakistan, while Sirmast Faiz is MPhil research student at Dr. Panjwani Centre for Molecular Medicine and Drug Research, Karachi, Pakistan.

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Published

2020-10-02

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Vol. 1 No. 2 (2020)

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How to Cite

Clinical characterization of Post-axial Polydactyly . (2020). Research Journal in Advanced Sciences, 1(2). https://doi.org/10.6084/rjas.v1i2.390