https://royalliteglobal.com/rjmhs/issue/feed Research Journal in Medical and Health Sciences 2022-08-04T21:14:30+00:00 Prof. Tom J. Webster t.webster@royalliteglobal.com Open Journal Systems <p style="text-align: justify;">Research Journal in Medicine and Health Sciences (RJMHS), is a peer-reviewed quarterly open access journal. The journal publishes experimental, translational and clinical approaches across all areas of biomedical sciences and clinical research and practice. primary objective to provide research and applications related to Medical &amp; Health Sciences. The Research Journal of Medical &amp; Health Sciences (RJMHS) aims to publish original research work that contributes significantly to enhance the scientific knowledge in Medical Sciences.&nbsp;</p> https://royalliteglobal.com/rjmhs/article/view/860 Renal function parameters and hematological indices among artisans occupationally exposed to lead in Suleja metropolis, Nigeria 2022-07-30T11:08:10+00:00 Aliyu Haruna Sani elharun014@gmail.com Collins Obinna Keke collinskeke2015@gmail.com Florence Harvey Harveyflorence14@gmail.com Ama Konamah nkonamah56@yahoo.com Tasallah Huawa Muhammad ahammad72@gmail.com <p>Lead exposure at work has been linked to significant health impacts, including a detrimental impact on organ functions, including nephrotoxicity and hematologic impairment. The above cross-sectional study was carried out to examine renal function status and hematological indicators of artisans working in the Suleja metropolis who had occupational lead exposure. There was a maximum of 137 persons studied: 67 artisans (car mechanics, generator repairers, petrol attendants, battery chargers, and spray painters) compared with 70 age-matched healthy control subjects between 17 and 50 years. Everyone had a 10ml venous blood sample drawn in order to determine biological markers (potassium, sodium, urea, uric acid, chloride and creatinine levels) and the complete blood count using standard laboratory methods. Results revealed that occupationally exposed artisans have significantly elevated blood lead of (82.25%, 37.6±0.8 µg/dL), White blood cell count (WBC) 8.5±1.4 x10<sup>9</sup>/L and decreased heamoglobin (Hb) (72.51%, 9.8±1.1 g/dL, P&lt;0.05), mean corpuscular volume (MCV) (76.2 ± 5.4 fL P&lt;0.05), mean corpuscular hemoglobin (MCH) (25.3±1.9 pg, P&lt;0.05) as compared with unexposed subjects (lead: 12.7±1.8 µg/dL, Hb: 14.3 ± 1.5 µg/dL. &nbsp;WBC: 6.5±1.8 x10<sup>9</sup>/L, MCV: 83.4 ± 2.7 fL, MCH: 28.7±1.4 pg; p&lt;0.05 in all cases). Significant elevations were also observed in the mean concentrations of serum urea (8.1±1.6 mmol/L), creatinine (1.3±0.3 mg/dL), sodium (163±32 mmol//L), potassium (6.1±1.3 mEq/L), as well as a considerable decrease in the mean serum chloride levels (86.7±18 mmol/L) of occupationally exposed artisans compared to unexposed subjects (110.5±21 mmol/L), indicating impaired renal and hematologic functions in occupationally exposed individuals.</p> 2022-08-04T00:00:00+00:00 Copyright (c) 2022 Aliyu Haruna Sani